Active Ingredient: Deltamethrin
Target Species: Cattle, sheep
Treats and Controls: Flies and lice on cattle and ticks, keds, lice and establshed blowfly on sheep
Administration Method: Pour on
Withdrawal Time: 17 days for cattle intended for meat and offal, zero hours for cattle producing milk for human consumption. 35 days for sheep intended for meat and offal, not permitted for use on sheep producing milk for human consumption.
Dosage for cattle: 10ml per ainmal
|Doses Per Pack
Dosage for sheep over 10 kg: 5 ml per animal
|Doses Per Pack
Dosage for lambs under 10 kg: 2.5 ml per animal.
|Doses Per Pack
Always read the label and all enclosed information for Spotinor before administering to animals!
Farm productivity and animal welfare can be greatly improved by early application of external parasite treatment such as Spotinor. If treatment is left until the fly population is already a problem it may already be too late. Spotinor uses deltamethrin which is a highly effective and fast acting insecticide that will help keep the fly population to a minimum.
The table below shows the untreated fly population compared to fly population after Spotinor has been used to treat cattle and sheep.
Summary of Product Characteristics
1 NAME OF THE VETERINARY MEDICINAL PRODUCT
Spotinor 10 mg/ml Spot-on Solution for cattle and sheep.
2 QUALITATIVE AND QUANTITATIVE COMPOSITION
Each ml contains
Deltamethrin 10 mg
For a full list of excipients, see section 6.1.
3 PHARMACEUTICAL FORM
A clear pale gold oily liquid.
4 CLINICAL PARTICULARS
4.1 Target Species
Cattle and Sheep.
4.2 Indications for use, specifying the target species
For the treatment and prevention of infestations by lice and flies on cattle; ticks, lice, keds and established blowfly
strike on sheep and lice and ticks on lambs.
For the treatment and prevention of infestations by both sucking and biting lice, including Bovicola bovis,
Solenopotes capillatus, Linognathus vituli and Haematopinus eurysternus in beef and dairy cattle.
Also as an aid in the treatment and prevention of infestations of both biting and nuisance flies including Haematobia irritans, Stomoxys calcitrans, Musca species and Hydrotaea irritans.
For the treatment and prevention of infestations by ticks Ixodes ricinus and by lice (Linognathus ovillus,
Bovicola ovis), keds (Melophagus ovinus) and established blowfly strike (usually Lucilia spp).
For the treatment and prevention of infestations by ticks Ixodes ricinus and by lice Bovicola ovis.
Do not use on convalescent or sick animals.
Do not use in cases of known hypersensitivity to the active substance or any of the excipients.
Extra-label use of the product in the non-target species dogs and cats can lead to toxic neurological signs (ataxia,
convulsions, tremors), digestive signs (hypersalivation, vomiting) and may be fatal.
4.4 Special warnings for each target species
To avoid resistance, the product should only be used if the susceptibility of the local fly population to the active
substance is assured.
Cases of resistance to deltamethrin have been reported in stinging and nuisance flies in cattle and lice in sheep.
The product will reduce the number of flies resting directly on the animal but it is not expected to eliminate all flies on
The strategic use of the product should, therefore, be based on local and regional epidemiological information
about susceptibility of parasites, and used in association with other pest management methods.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
- too frequent and repeated use of ectoparasiticides from the same class over an extended period of time;
- underdosing which may be due to underestimation of bodyweight, misadministration of the product, or lack of
calibration of the dosing device.
If clinical signs do not resolve following treatment, the diagnosis should be revised.
4.5 Special precautions for use
(i) Special precautions for use in animals
The product is for external use only.
Do not apply on or near the animal’s eyes and mucous membranes.
Care should be taken to prevent licking of the product.
Avoid use of the product during extremely hot weather and ensure animals have adequate access to water.
The product should only be administered onto undamaged skin as toxicity is possible due to absorption from major skin lesions.
However, signs of local irritation may occur after treatment as skin may be already affected by infestation.
(ii) Special precautions to be taken by the person administering the product to the animal
Persons with known hypersensitivity to the product or one of its components should avoid contact with the veterinary
Wear protective clothing including waterproof apron and boots and impervious gloves when either applying the
product or handling recently treated animals.
Remove heavily contaminated clothing immediately and wash before use.
Wash splashes from skin immediately with soap and plenty of water.
Wash hands and exposed skin after handling this product and before meals.
In case of contact with eyes, rinse immediately with plenty of clean, running water and seek medical advice.
In case of accidental ingestion, wash out mouth immediately with plenty of water and seek medical advice.
Do not smoke, drink or eat while handling the product.
This product contains deltamethrin which may produce tingling, itchiness and blotchy redness on exposed skin. If you
feel unwell after working with this product, consult your doctor and show this label.
To the physician:
Advice on clinical management is available from the National Poisons Information Service.
(iii) Other Precautions
Deltamethrin is very toxic to dung fauna, aquatic organisms and honey bees, is persistent in soils and may accumulate in sediments.
The risk to aquatic ecosystems and dung fauna can be reduced by avoiding too frequent and repeated use of
deltamethrin (and other synthetic pyrethroids) in cattle and sheep, e.g. by using a single treatment per year on the same pasture.
The risk to aquatic ecosystems will be further reduced by keeping treated cattle away from water bodies for four weeks after treatment.
4.6 Adverse reactions (frequency and seriousness)
Squamosis and pruritus have been seen in some cattle during the 48 hours after treatment.
4.7 Use during pregnancy, lactation or lay
Laboratories studies (rat, rabbits) have not produced any evidence of teratogenic or embryotoxic effects.
No studies have been conducted with the product in pregnant cows and ewes.
Use of the product during pregnancy and lactation in cows and ewes must be according to the benefit/risk assessment made by the responsible veterinarian.
4.8 Interaction with other medicinal products and other forms of interaction
Do not use with any other insecticide or acaricide.
4.9 Amounts to be administered and administration route
For external use.
Cattle: 100 mg of deltamethrin per animal corresponding to 10 ml of product.
Sheep: 50 mg of deltamethrin per animal corresponding to 5 ml of product
Lambs (under 10 kg bodyweight or 1 month of age): 25 mg of deltamethrin per animal corresponding to 2.5 ml of
Apply a single dose with the special 'Squeeze 'n' Pour' dispenser pack or the Spot-On Applicator in one spot on the mid-line of the back at the shoulders.
For blowfly strike on sheep, see following specific indication directions.
Lice on cattle:
One application will generally eradicate all lice.
Complete clearance of all lice may take 4 - 5 weeks during which time lice hatch from the eggs and are killed. A very few lice may survive on a small minority of animals.
Flies on cattle:
For the treatment and prevention of infestations by biting and non-biting flies. Where horn-flies
predominate, treatment and prevention of infestations can be expected for 4 - 8 weeks. Treatment for flies should not be repeated within four weeks.
Ticks on sheep:
Application to the mid-point of the shoulders will provide useful treatment and prevention of infestations by ticks attaching to animals of all ages, for up to 6 weeks after treatment.
Keds and lice on sheep: Application to the mid-point of the shoulders of sheep in short or long fleece will reduce the
incidence of a biting louse or ked infestation over a 4 - 6 week period after treatment.
It is advisable to:
- treat shortly after shearing (animals with short fleece),
- keep treated sheep separated from untreated sheep to avoid re-infestation.
N.B. For treatment and prevention of infestations by ticks, keds and lice on sheep, the fleece should be parted and the Spot-On applied to the skin of the animal.
Established blowfly strike on sheep:
Apply directly to the maggot infected area as soon as the fly strike is seen.
One application will ensure blowfly larvae are killed in a short time. In the case of more advanced strike lesions, clipping out of stained wool before treatment is advisable.
Lice and ticks on lambs:
Application to the mid-point of the shoulders will provide useful treatment and prevention of infestations by ticks for up to 6 weeks after treatment, and will reduce the incidence of biting lice over a 4-6 week period after treatment.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Some adverse effects have been seen following overdose.
These include paraesthesia and irritation in cattle, as well as intermittent or attempted urination in young lambs. These have been shown to be mild, transient and resolve without treatment.
4.11 Withdrawal Period(s)
Meat and offal: 17 days
Milk: zero hours
Meat and offal: 35 days
Milk: Not authorised for use in ewes producing milk for human consumption.
5 PHARMACOLOGICAL or IMMUNOLOGICAL PROPERTIES
Ectoparasiticide for topical use, including insecticides. Pyrethrins and pyrethroids.
5.1 Pharmacodynamic properties
Deltamethrin is a synthetic pyrethroid possessing insecticidal and acaricidal activity.
It is one of a large family of pyrethroid esters which have evolved as synthetic analogues of the original insecticidal extracts isolated from powdered pyrethrum flowers.
Deltamethrin is an alpha- cyano pyrethroid and is a member of the second generation of pyrethroids in which the overall stability of the molecule is improved with correspondingly increased resistance to photo- and bio-degradation and enhanced insecticidal activity.
It is more potently toxic to insects and acarines because of the slower rate of metabolism.
The precise mode of insecticidal activity of pyrethroids remains uncertain, but they are potent neurotoxins in insects,
causing failure in sensory coordination and disorganised motor activity, hence the 'knock-down' effect.
Pyrethroids are metabolised through oxidative and neurotoxic pathways far more rapidly in mammals, so that neurotoxic effects can only occur at dosages which are many orders of magnitude greater than those required for ectoparasitic activity.
Two physiological mechanisms are likely to contribute to deltamethrin-resistance: mutation of the molecular
deltamethrin target or through metabolic enzyme glutathione-S-transferases.
5.2 Pharmacokinetic properties
After dermal application, deltamethrin is slightly absorbed through skin of cattle and sheep.
Pyrethroids are metabolised through oxidative and neurotoxic pathways.
The main route of excretion of the absorbed amount in the target animal is the faeces.
5.3 Environmental properties
Deltamethrin has the potential to adversely affect non-target organisms, both in water and in dung.
Following treatment, excretion of potentially toxic levels of deltamethrin may take place over a period of 4 weeks. Faeces containing deltamethrin excreted onto pasture by treated animals may reduce the abundance of dung feeding organisms which may impact on the dung degradation.
Deltamethrin is very toxic to dung fauna, aquatic organisms and honey bees, is persistent in soils and may accumulate in sediments.
6 PHARMACEUTICAL PARTICULARS
6.1 List of excipients
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf-life after first opening the immediate packaging: 6 months
6.4 Special precautions for storage
Store the dispenser bottle in the outer carton in order to protect from light.
Do not freeze.
6.5 Nature and composition of immediate packaging
250 and 500 ml clear high-density polyethylene bottle with internal graduated calibration chamber and a white screw
1 litre and 2.5 litre white high density polyethylene back pack for use with a suitable dosing device and a white screw
Not all pack sizes may be marketed.
6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials
Dangerous to fish and other aquatic organisms. Do not contaminate ponds, waterways or ditches with the product or
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
7 MARKETING AUTHORISATION HOLDER
Norbrook Laboratories Ltd
8 MARKETING AUTHORISATION NUMBER(S)
9 DATE OF THE FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION
Date of first authorisation: 5th September 2014
Sheep Pour-ons and spot-ons
Pour-ons and spot-ons need to be applied accurately and each manufacturer may recommend subtle differences. Use appropriate and calibrated guns, always clean with warm soapy water and then rinse after use.
Store in a safe dry place.
When treating sheep with these products, make sure they are applied along the back line.
If placed to one side, the product will not spread evenly around the body.
No pour-on or spot-on is effective against sheep scab.
The Four Stroke Method: The four stroke method ensures the pour-on is applied evenly by applying a quarter of the application at a time in four simple strokes.
1) 1/4 applied from between the shoulders to middle of back
2) 1/4 applied from middle of back to top of animals tail
3) 1/4 applied from one side of the animals tail down the crutch
4) 1/4 applied from other side of tail down the other crutch
These should be applied along the length of the flattest part of the animal’s back, from the withers to the tail head.
In general, animals should not be treated when the hair is wet or if rain is anticipated within two hours of treatment. However, some products are waterproof and can be used on wet animals.
Areas of damaged skin should be avoided, as should areas contaminated with mud or manure.
What is deltamethrin?
Deltamethrin is an insecticide belonging to the pyrethroid family.
Pyrethroids are the man-made versions of pyrethrins, natural insecticides from chrysanthemum flowers.
Deltamethrin was first described in 1974 and entered the marketplace in 1978.
Deltamethrin is in a variety of products used to kill a wide range of insects.
How does deltamethrin work?
Deltamethrin can kill insects by direct contact or if they eat it.
It disrupts their normal nervous system function.
It is less toxic to mammals due to their higher body temperature, larger body size, and decreased sensitivity to the chemical.
Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately.
Due to Brexit we are temporarily unable to ship to the UK. Shipping to Northern Ireland will remain in place.
|Ireland (ROI & NI)
|EU (Mainland Only)
|2-4 Working Days
|4-6 Working Days
Some products have an extended delivery time, this is noted on the products.
|Orders Under €129
|Orders Over €129
|Ireland (ROI & NI)
A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages.
There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.
We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.
All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.
Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.
If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.
All returns should be complete which includes boxes, manuals and accessories that may have been included with the order.
All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.
We accept no responsibility for goods damaged or lost while in transit to us.
We have partnered with DPD to make your returns process easy and secure. simply follow the steps below and bring your package to an official DPD pickup point.
1) All returns must be accompanied with a fully filled out returns form which can be downloaded here.
3) Bring your package to a DPD pickup point. To find your nearest drop off point here.
Once the returned product has been received into our warehouse and been fully inspected a refund will be issued.
If you choose not to use the DPD returns service we recommend that you use a method that can be tracked.
For the return of bulk products please contact us at firstname.lastname@example.org
First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.
How do I begin the returns process?
If you wish to begin the return process, please email us at email@example.com and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.
Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.
Once the returned product has been returned to us and fully inspected a refund will be issued.
Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.
Would you like to send this voucher to the recipient via email?Yes No