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Curafluke 5% (Rafoxanide, Fenbendazole)
Curafluke 5% (Rafoxanide, Fenbendazole)

Curafluke 5% (Rafoxanide, Fenbendazole)

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Curafluke 5% oral solution is a broad spectrum flukicide and wormer for sheep and cattle. Curafluke 5% is used for the treatment and control of stomach worms, lungworms, mature and immature fluke, in sheep and beef cattle.

Active Ingredient: Rafoxanide, Fenbendazole

Target Species: Cattle, sheep

Treats and Controls: Stomach worms, lungworms, mature and immature fluke

Administration Method: Oral drench

Withdrawal Time: 60 days for cattle intended for meat and offal, not permitted for use on cattle producing milk for human consumption. 54 days for sheep intended for meat and offal, not permitted for use on sheep producing milk for human consumption

Dosage for cattle: 11.25 ml per 50 kg of bodyweight

Body Weight Dose Volume Number of full doses per pack
1 Litre 2.5 Litre 5 Litre
50kg 11.25 ml 89 222 444
100kg 22.5 ml 44 111 222
150kg 33.75 ml 30 74 148
200kg 45 ml 22 56 111
250kg 45 ml 18 44 89
300kg 56.25 ml 15 37 74
350kg 78.75 ml 13 32 63
400kg 90 ml 11 28 56
450kg 101.25 ml 10 25 49
500kg 112.5 ml 9 22 44
550kg 123.75 ml 8 20 40
600kg 135 ml 7 19 37

Dosage for sheep: 1.5ml per 10kg Bodyweight

Body Weight Dose Volume Number of full doses per pack
1 Litre 2.5 Litre 5 Litre
10kg 1.5 ml 637 1667 3333
20kg 3 ml 333 833 1667
30kg 4.5 ml 222 516 1111
40kg 6 ml 167 417 833
50kg 7.5 ml 133 333 667
60kg 9 ml 111 278 556
70kg 10.5 ml 95 238 476

Always read the label and all enclosed information for Curafluke 5% Oral Suspension before administering to animals!

Key Features of Curafluke 5%

  • Oral solution
  • Broad spectrum flukicide and wormer for sheep and cattle. 
  • Treats and controls  stomach worms, lungworms, mature and immature fluke, in sheep and beef cattle.
  • Withdrawal time   MEAT AND OFFAL            CATTLE   60 days      Sheep  54 days

How Livestock Contracts Liver Fluke

Animals are infected by ingesting encapsulated larvae (metacercariae) on contaminated grass. Typically,individual farms will have wet “flukey areas” that should not be used or grazed at times of the year when metacercariae are likely to be present, i.e. late summer to winter (depending on climatic conditions). However,cattle and sheep often graze on such areas. Therefore, it cannot be assumed that liver fluke infection is absent from any area of Ireland.

This product is only licensed for sale within the Republic of Ireland


Click here to Download Data Sheet

Health Products Regulatory Authority

Summary of Product Characteristics

Curafluke 5% w/v Oral Drench

Each 1 ml of suspension contains:
Active Substance
Fenbendazole 50.00 mg
Rafoxanide 50.00 mg

Propyl parahydroxybenzoate 0.10 mg
Methyl parahydroxybenzoate 1.00 mg
Quinoline yellow (E104) 0.09 mg
For a full list of excipients, see section

Oral Suspension.
A pale, lemon suspension.

4.1 Target Species

Cattle and sheep.

4.2 Indications for use, specifying the target species
Curafluke 5% Oral Drench permits a three way activity against Fluke, Lungworms and Stomach Worms in Cattle and Sheep.
It is a broad spectrum anthelmintic for the treatment of benzimidazole susceptible mature and immature stages of nematodes and cestodes of the gastrointestinal and respiratory tracts of cattle and sheep.
Rafoxanide is active against immature and mature Fasciola hepatica (mature and immature over 8 weeks of age).

 Cattle and Sheep:
Haemonchus sp.
Ostertagia sp.
Trichostrongylus sp.
Cooperia sp.
Nematodirus sp.
Bunostomum sp.
Trichuris sp.
Strongyloides sp.
Oesophagostomum sp.
Dictyocaulus sp.
Moniezia sp.
Fasciola hepatica (mature and immature over 8 weeks of age).
The product has a good therapeutic effect against type II Ostertagiasis.

4.3 Contraindications

4.4 Special warnings for each target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy.
 Too frequent and repeated use of anthelmintics from the same class over an extended period of time. 
 Underdosing, which may be due to under-estimation of the bodyweight, mis-administration of the product or lack of calibration of the dosing device (if any).
As with other anthelmintics, veterinary advice should be sought on appropriate dosing programmes and stock management to achieve adequate parasite control and reduce the likelihood on anthelmintics resistance developing. If the product does not achieve the desired clinical effect, other diseases, nutritional diseases or anthelmintic resistance may be involved.

4.5 Special precautions for use
Special precautions for use in animals

Where a dosing gun is used to administer the product care must be taken to avoid the occurrence of dosing gun pharyngitis.
Special precautions to be taken by the person administering the veterinary medicinal product to animals Wash hands after use.

4.6 Adverse reactions (frequency and seriousness)
None known.

4.7 Use during pregnancy, lactation or lay
Fenbendazole and rafoxanide are safe for use during pregnancy. See section 4.11

4.8 Interaction with other medicinal products and other forms of interactions
None known.

4.9 Amounts to be administered and administration route
For oral administration in cattle and sheep.
For sheep, the recommended therapeutic dose is 7.5 mg fenbendazole and
                                                                               7.5 mg rafoxanide per kilogram bodyweight.
For cattle, the recommended therapeutic dose is 11.25 mg fenbendazole and
                                                                              11.25 mg rafoxanide per kilogram bodyweight.
Shake well before use
Estimate bodyweight carefully.
Use only properly calibrated dosing equipment.
Practical dosage recommendations are as follows:

Bodyweight (Kg)          Dose (ml)
50                                  11.25
100                                22.5
400                                90.0
> 400 kg                        11.25 ml/50 kg
10                                   1.5 
50                                   7.5

At 2 months after housing, when dosing cattle for worms and adult fluke, a lower dose of 7.5 mg/kg can be used i.e. 7.5 ml per 50kg bodyweight,
30 ml per 200 kg or
75 ml per 500 kg.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Curafluke 5% Oral Drench is well tolerated in cattle at three times the recommended dosage

4.11 Withdrawal period(s)
Cattle - 60 days.
Animals intended for human consumption may be slaughtered only from 60 days after the last treatment.
Sheep - 54 days.
Animals intended for human consumption may be slaughtered only from 54 days after the last treatment.

Milk: Not authorised for use in animals producing milk for human consumption including during the dry period.
Do not use during the last trimester of pregnancy in heifers which are intended to produce milk for human consumption.
Do not use within 1 year prior to the first lambing in ewes intended to produce milk for human consumption.

ATC Vet Code:

Pharmacotherapeutic Group:
combinations of benzimadazoles and related substances.

Curafluke 5% Oral Drench is a broad spectrum anthelmintic.

6.1 List of excipients

Xanthan gum (E415)
Quinoline yellow (E104)
Simethicone emulsion
Propyl parahydroxybenzoate (E216)
Methyl parahydroxybenzoate (E218)
Polysorbate 80 Sodium citrate (E331)
Sodium metabisulphite (E223)
Citric acid monohydrate
Purified water

6.2 Major incompatibilities
None known.

6.3 Shelf-life
Shelf-life of the veterinary medicinal product as packaged for sale:
White HDPE containers: Three years

6.4 Special precautions for storage
Store below 25°C.
Protect from light and frost.

6.5 Nature and composition of immediate packaging 
1L (jerrican, backpack),
2.5L (jerrican, backpack) or
5L (jerrican, backpack)
HDPE white containers with a HDPP screw cap and a wood pulp PVDC liner.
The product may be marketed with or without an outer carton.
Not all pack sizes may be marketed

6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials derived from the use of such products
Unused product or waste material should be disposed of in accordance with current practice for pharmaceutical waste under national waste disposal regulations

Univet Limited
Co. Cavan.


Date of first authorisation: 05 September 1997
Date of last renewal: 04 September 2007 

January 2018

Drench correctly
Sheep Oral Drench

The drenching technique is a vital part of ensuring that the wormer does its job effectively.
Make sure the sheep are properly restrained and cannot leap around when they are being drenched so they swallow the whole amount.
Sheep can also suffer serious injury, or even death, if they are unrestrained and the gun penetrates the tissues at the back of the mouth.
Place a hand under the head and tilt slightly to the side.
Slot the nozzle in the gap between molar and incisor teeth and then over the back of the tongue.
If the wormer is just put into the mouth, it will bypass the rumen as it escapes down the oesophageal groove and will be less effective.
This is particularly important for white (BZ) drenches.

Dosing Weigh – do not guess Underestimating the weight of sheep is a common cause of underdosing. Select and weigh the biggest sheep in the group to determine the correct dose. If there is a wide range of weights, consider splitting the group, then weigh the heaviest in each section. Do not forget to check that the weigh crate is accurate before starting!

Calibrate and maintain the drench gun
Always check the gun is delivering the right amount before you drench. Remove the plunger from a 10 ml syringe, put a thumb over the end and squirt the dose into it, making sure there are no air bubbles left. Adjust the gun until the dose delivered is correct. Drenching guns should also be well maintained and replaced regularly. Clean with warm soapy water after use and check springs and tubes to make sure there are no kinks that will form air bubbles.

Withholding food
Research has shown that the efficacy of the white (BZ) and clear (AV) drenches can be improved by withholding food for 12–24 hours before treatment. It is not advised to deprive heavily pregnant ewes of food, so if you treat this class of stock with anthelmintics, you may wish to use yellow drenches (LV) because their efficacy is less dependent on rumen fill.

Wormers should be stored securely, away from direct sunlight at 4–25°C. Check the use-by date and, once open, use within the time shown on the packaging. Shake white (BZ) products well before use.

 Cattle Oral drenches
Oral drenching guns are designed to deliver the treatment towards the back of the mouth over the tongue, so the entire dose is swallowed at once to optimise efficacy.
• Make sure animals are properly restrained, with their head held up
• Slide the nozzle of the dosing gun in the side of the mouth and over the tongue so that the entire dose is swallowed immediately
• Drenching equipment must be correctly calibrated and in good working order
• Calibrate the gun using the product just before treatment starts by delivering two or more doses into a graduated measuring cylinder. 
Faulty equipment, or attempting to dose too quickly, may mean that the barrel of the gun does not fill properly or that the liquid is full of bubbles.

Delivery Information

Delivery Service

Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately. 

Due to Brexit we are temporarily unable to ship to the UK. Shipping to Northern Ireland will remain in place.

Delivery Times
Ireland (ROI & NI) EU (Mainland Only)
2-4 Working Days 4-6 Working Days

Some products have an extended delivery time, this is noted on the products.

Delivery Rates

Country Orders Under €129 Orders Over €129
Ireland (ROI & NI) €7.99 €0.00
Austria €24.99 €17.00
Belgium €21.99 €14.00
Czech Republic €24.99 €17.00
Denmark €24.99 €17.00
Finland €36.99 €29.00
France €21.99 €14.00
Germany €21.99 €14.00
Hungary €28.99 €21.00
Italy €34.99 €23.00
Luxenburg €21.99 €14.00
Netherlands €21.99 €14.00
Poland €21.99 €17.00
Portugal €36.99 €29.00
Slovakia €28.99 €21.00
Slovenia €28.99 €21.00
Spain €34.99 €27.00
Sweden €34.99 €27.00


A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages.

There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.

Agridirect Returns Policy

We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.

All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.

Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.

If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.

All returns should be complete which includes boxes, manuals and accessories that may have been included with the order.

All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.

We accept no responsibility for goods damaged or lost while in transit to us. 

How do I return a product?

We have partnered with DPD to make your returns process easy and secure. simply follow the steps below and bring your package to an official DPD pickup point.

1) All returns must be accompanied with a fully filled out returns form which can be downloaded here.

2) To print off your return label click here or visit and follow the on-screen instructions. Make sure and use your order number as your reference.

  • Select “Continue as Guest”
  • Select “Agridirect” from the drop-down menu
  • Select your reason for returning
  • Select the size of the package you wish to return
  • Accept DPD’s terms and conditions
  • Fill in your payment details
  • Fill in your own details
  • Follow the instructions to print off your label

3) Bring your package to a DPD pickup point. To find your nearest drop off point here.

Once the returned product has been received into our warehouse and been fully inspected a refund will be issued.

If you choose not to use the DPD returns service we recommend that you use a method that can be tracked.

For the return of bulk products please contact us at

I have received a damaged product from you, what should I do?

First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.

How do I begin the returns process?

If you wish to begin the return process, please email us at and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.

Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.


Once the returned product has been returned to us and fully inspected a refund will be issued.

Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.



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