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Levacide Injection 500ml (Levamisole)

Levacide Injection 500ml (Levamisole)

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Levacide Injection 75 mg/ml is a broad spectrum athelmintic used for the treatment and control of infections caused by lungworms and gastro intestinal worms in sheep and cattle. As opposed to using a pour on, Levacide Injection can be used in wet weather without the worry of the livestock not being properly treated.

Active Ingredient:Levamisole

Target Species: Cattle, sheep

Treats and Controls: Gastro-intestinal roundworms, lungworms,

Administration Method: Subcutaneous injection

Withdrawal Time: 14 days for animals intended for meat and offal, not permitted for use on animals producing milk for human consumption.

Dosage rate for cattle:1 ml per 10 kg of bodyweight

Bodyweight in kgDose in mlFull doses per bottle

Dosage rate for sheep: 1 ml per 10 kg bodyweight

Bodyweight in kgDose in mlFull doses per bottle

Always read the label and all enclosed information for Levacide Injection before administering to animals!

After being housed for the winter cattle's immunity to worms from the year before is lowered, this means that lungworm disease and gut worms can infect grazing cattle and spread easily throughout your herd during the summer months. Lungworm and gut worm infection can have a highly negative effect on the health of your herd which causes not only weight loss and even in severe cases death, but also has a strong effect on the profit margins of the farm.Levacide Pour-on solution is easy to use and highly effective against these parasites.

Why use an injection over a pour?

  • Injections are the most reliable way to maximise the effect of the active ingredient
  • Injections guarantee the active ingredient is delivered rapidly and in high concentration
  • With injections, factors such as skin and coat thickness, spillage of product and weather do not affect dosage
Signs and effects of infected cattle
Infection:Gut Worm

Symptoms: Diarrhoea, decreased appetite, loss of weight

Effects: Gutworm can cause severe damage to the stomach and small intestine which will cause parasitic gastroenteritis, this will not only negatively effect the health of the animal but will effect the profitability for the farmer.

Infection: Lungworm

Symptoms:Short, sharp cough that becomes worse with exercise, in sever cases the animal will have obvious difficulty breathing.

Effects:Lung worm infections cause a highsusceptibility to respiratory viruses and bacteria. Infected cattle are prone to contracting severe bronchial pneumonia which left untreated can lead to death.

Features of Levacide Injection

  • 75 mg/ml is a broad spectrum athelmintic
  • Used for the treatment and control of infections caused by lungworms and gastro intestinal worms
  • Used on both sheep and cattle.
  • Levacide Injection can be used in wet weather
Data Sheet

Levacide Injection 75 mg/ml

For a full list of excipients see section 6.1.
Each ml contains:
Active Substance
Levamisole (as levamisole hydrochloride) 75 mg
Methyl Parahydroxybenzoate (E218) 1.5 mg
Sodium Metabisulphite 1.5 mg

Solution for injection.
A clear colourless sterile solution.

4.1 Target Species
Cattle, Sheep

4.2 Indications for use, specifying the target species
Levacide Injection is a broad spectrum anthelmintic for use in the treatment and control of nematode infections. It
should be used in cases of parasitic gastro-enteritis and lungworm disease caused by mature and developing immature
forms of those organisms sensitive to treatment with Levamisole Hydrochloride including the following:
Lungworms (adult and larval stages): Dictyocaulus spp.
Gastro-intestinal worms (adult and larval stages):
Trichostrongylus spp.
Cooperia spp.
Ostertagia spp. (except inhibited Ostertagia larvae in cattle)
Haemonchus spp.
Nematodirus spp.
Bunostomum spp.
Oesophagostomum spp.
Chabertia spp.

4.3 Contraindications
Do not use in animals known to be hypersensitive to Levamisole.
Each ml contains:
Active Substance
Levamisole (as levamisole hydrochloride) 75 mg
Methyl Parahydroxybenzoate (E218) 1.5 mg
Sodium Metabisulphite 1.5 mg

4.4 Special warnings for each target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and
could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing which may be due to underestimation of bodyweight, misadministration of the product, or lack of
calibration of the dosing device.
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal
Egg Count Reduction Test). Where the results of the tests strongly suggest resistance to a particular anthelmintic, an
anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

4.5 Special precautions for use
Special precaution(s) for use in animals
After treatment animals should be moved to clean pasture in order to prevent re-infection. Where this is not done,
further dosing at 21 day intervals may be necessary.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
When using, do not eat, drink or smoke.
Wash hands and exposed skin before meals and after work.
Wash splashes from eyes and skin immediately.
Take off immediately any contaminated clothing.
Levamisole can cause idiosyncratic reactions and serious blood disorders in a very small number of people. If
symptoms such as dizziness, nausea, vomiting or abdominal discomfort are experienced when using the product, or
sore mouth/throat or fever occur shortly afterwards, then medical advice should be sought immediately.

4.6 Adverse reactions (frequency and seriousness)
Although normally non-irritant, Levacide Injection may occasionally cause local reaction at the site of injection. This
should resolve naturally in a short period of time.

4.7 Use during pregnancy, lactation or lay
The product can be safely administered to pregnant or lactating animals. However, care should be taken to avoid
unnecessary stress when handling heavily pregnant animals.

4.8 Interaction with other medicinal products and other forms of interaction
Concurrent treatment with products containing organophosphorus compounds or diethylcarbamazine citrate should be
avoided. These compounds should not be administered within a period of 14 days before or after treatment with
Levamisole. Levamisole is not affected by benzimidazole resistance.

4.9 Amounts to be administered and administration route
Levacide Injection should be administered by subcutaneous injection at a rate of 7.5 mg Levamisole hydrochloride per
kg bodyweight (1 ml/10 kg bodyweight).
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible. If animals are
to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed
accordingly, in order to avoid under- or overdosing.
Use properly calibrated dosing equipment.
The veterinary surgeon should give advice regarding appropriate dosing programmes and stock management to achieve
adequate parasite control.

4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Levacide Injection is safe for use in cattle and sheep at the recommended dosages. However, if recommended doses
are exceeded animals may exhibit signs of impaired motor function such as muscle tremors and increased salivation,
which are of a temporary nature.

4.11Withdrawal Period(s)
Not to be used in cattle and sheep producing milk for human consumption. Cattle and sheep may be slaughtered for
human consumption only after 14 days from the last treatment.

Pharmacotherapeutic group: Anthelmintics, imidazothiazoles
ATCvet code: QP52AE01

5.1 Pharmacodynamic properties
Levamisole Hydrochloride is the levo isomer of dl 2, 3, 5, 6-Tetrahydro-6-phenyl-imidazo (2,l-b) thiazole
Hydrochloride. Levamisole was found to be active against adult and immature gastro-intestinal and pulmonary
nematodes when administered to experimentally infected animals by the oral, subcutaneous, intramuscular or
intraperitoneal routes. It is thought to act by paralysing the susceptible parasites which are then expelled from the
alimentary canal.

6.1 List of excipients
Methyl Parahydroxybenzoate (E218)
Sodium Citrate
Citric Acid Anhydrous
Sodium Metabisulphite
Disodium Edetate
Water for Injection

6.2 Incompatibilities
None known.

6.3 Shelf-life
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years
Shelf-life after first opening the immediate packaging: 28 days

6.4 Special precautions for storage
Do not store above 25oC.
Protect from light.

6.5 Nature and composition of immediate packaging
Marketed in multidose collapsible polyethylene containers of 100 ml, 250 ml and 500 ml capacity which are sealed
with nitryl closures and aluminium caps.
Not all pack sizes may be marketed.

6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be
disposed of in accordance with local requirements.

Norbrook Laboratories Ltd.,
Station Works,
Co. Down, BT35 6JP,
Northern Ireland.

VPA 10999/37/1

30th september 2009



Delivery Information

Here at Agridirect we have joined forces with DPD to ensure all packages are delivered promptly and safely to you. We ship to all mainland countries within the EU. Deliveries take place Monday to Friday excluding bank holidays. Once your order has been dispatched from our warehouse you will be notified by email. If there is a delay with your order for any reason you will be contacted immediately. 

Delivery Times
Ireland (ROI & NI)United Kingdom (Mainland Only)EU (Mainland Only)
1-3 Working Days2-4 Working Days4-6 Working Days

Some product have an extended delivery time, this is noted on the products.

Delivery Rates

Delivery Rates
CountryOrders Under €70Orders Over €70
Ireland (ROI & NI)€4.99€0.00
Czech Republic€17.99€13.00
United Kingdom (Mainland Only)€14.99€10.00



A selection of the products we sell are only licensed for sale within the Republic Of Ireland and can not be shipped outside of the country. These products are noted as only being available within the Republic of Ireland on the individual product pages

There may be an addition charge on certain bulky items. This charge will be clearly marked on an applicable products and will be explained on the checkout page before payment has been made.



Returns Policy

We’re sorry your purchase didn’t work out. But don’t worry; we have a great returns policy to help you out.

All purchases can be returned to us within 14 days of delivery and returned goods must be received within 14 days from the date you informed us of the return.

Purchases may be opened for inspection but must not be used and must be repackaged securely in the original packaging if you wish to return it.

If we discover goods have been used or there has been a loss in value of the goods due to damage to the goods, while in your care or whilst being returned to us, we will reduce the amount refunded, which may amount to the full cost of the product, to cover loss of value of goods.

We accept no responsibility for goods damaged or lost while in transit to us. 

The cost of the return, including all packaging and freight, lies solely with the consumer.

I have received a damaged product from you, what should I do?

First off, if you have received a damaged electrical product from us, do not plug it in. Any electrical products that are plugged in are deemed ‘as used and accepted’ and are not accepted as returns. All damages must be reported to us via phone or email within 24hours of receipt of goods. Please ensure you check your items upon delivery.

How do I begin the returns process?

If you wish to begin the return process, please email us at and ensure the following information is included in your email. Your name, phone number, Order id, the item you wish to return, reason for return and if the product is damaged we require photos of the product.

Once you have sent us all required information a member of our team will assess your claim and will contact you as soon as possible. Please hold off on returning products until a member of our team has called you to confirm.



All returns must be the complete product which includes boxes, manuals and accessories that may have been include with the order.

All returns must be packaged appropriately for shipping, we will not accept responsibility for damages or loss which occur during shipping of a return product.

Address: Please ship the product to the following address: Agridirect, Drumrahan Retail, Church Street, Ballyconnell, Co Cavan


Once the returned product has been returned to us and fully inspected a refund will be issued.

Please Note: A typical timeline for a refund to show in your account is up to 10 working days from the date processed, depending on your bank.

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